Selank
Nootropic Anxiolytic Peptide
Best For
Stress-related cognitive decline, anxious-pattern clients seeking non-sedating support
GABA
Primary receptor system modulated
BDNF
Key neurotrophic factor upregulated
0
Sedation or dependence risk
How It Works
Selank is a synthetic analogue of the endogenous immunomodulatory peptide tuftsin, extended with a Pro-Gly-Pro stabilizing sequence. It enhances GABAergic neurotransmission by modulating GABA-A receptor sensitivity, producing anxiolytic effects without the sedation or dependence associated with benzodiazepines. Selank also upregulates brain-derived neurotrophic factor (BDNF) expression in the hippocampus and prefrontal cortex, supporting synaptic plasticity and cognitive resilience under stress.
Key Research Areas
Anxiety Reduction
GABAergic modulation produces calm focus without sedation or cognitive dulling
Cognitive Support
BDNF upregulation enhances memory consolidation and learning under stress
Immune Modulation
Tuftsin-derived structure supports balanced immune signaling
Stress Resilience
Stabilizes emotional reactivity during high-demand periods
Research Highlights
- Anxiolytic effect without sedation, tolerance, or withdrawal
- Tuftsin analogue with dual neuro-immune signaling benefits
Formulation Notes
Common concentrations referenced in published clinical studies:
[SK5]5mg[SK11]10mgCategory
Cognitive enhancement and neuroprotection through targeted peptide signaling. These compounds modulate BDNF, NGF, and GA...
Explore Mind category →Educational Content. This compound profile is for informational purposes only. Not intended as medical advice, diagnosis, or treatment.
Evidence reviewed: March 2026